Clinical Outcomes of Unprotected Left Main Stem Stenting: An Observational Single-Centre Study

Authors

  • Muhammad Abdur Rauf Peshawar Medical College, Peshawar, KPK, Pakistan.
  • Jehandad Khan MTI Mardan Medical complex, KPK, Pakistan.
  • Mehmood ul Hssan Hayatabad Medical Complex, KPK, Pakistan.
  • Sarmad Raza Hayatabad Medical Complex, KPK, Pakistan.
  • Imad Uddin Hayatabad Medical Complex, KPK, Pakistan.
  • Samiullah Hayatabad Medical Complex, KPK, Pakistan.

Keywords:

Percutaneous Coronary Intervention, Drug-Eluting Stents, Left Main Stem, Stening.

Abstract

Objective: Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) has become a common treatment approach for patients with unprotected left main stem (LMS) disease. This procedure involves the use of stents to open up blockages in the left main coronary artery, a critical vessel that supplies blood to a large portion of the heart. This study aims to know the clinical outcomes of percutaneous intervention (PCI) with drug eluting stents (DES) in patients with unprotected left main stem disease.

Methodology: This single-centre, prospective, observational study was conducted on 133 patients, who underwent PCI using DES to an unprotected LMS at Kuwait teaching Hospital Peshawar, between 2018 to 2022. Patients were followed in OPD and clinics or they were traced through calls at monthly and yearly intervals, after the procedure. A team, which comprised of a cardiac interventionist and a cardiac surgeon, scrutinised patients for the eligibility of either procedure. Ethical Committee approval was granted by the Institutional Ethics committee.

Results: At 1month follow up, the composite end point occurred in 13 (11.58%) patients, whereas individual secondary end points including death from all-cause mortality was reported in 5 (4.7%), stroke in 1 (0.9 %), MI in 4 (3.73 %) and repeat vascularisation in 3 (2.25%) patients. The annual incidence of composite end point occurred in 27.58%patients, whereas individual secondary end points including death from all-cause mortality was reported in 10 (8.27%), stroke in 3 (2.25 %), MI in 09 (6.76%) and repeat vascularisation in 11 (10.3%) patients.

Conclusion: PCI to LMS can be performed safely in centres having no cardiac surgery backup and newer imaging modalities with results comparable to the centres having the luxury of such facilities, provided that operators are skilled enough with sufficient expertise and knowledge.

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Published

25.04.2024

How to Cite

Rauf, M. A., Khan, J., Hssan, M. ul, Raza, S., Uddin, I., & , S. (2024). Clinical Outcomes of Unprotected Left Main Stem Stenting: An Observational Single-Centre Study. Pakistan Journal of Cardiovascular Intervention, 4(1), 17–22. Retrieved from https://pjcvi.com/index.php/ojs/article/view/35